Early increases in plasma bile acids post Roux-en-Y gastric bypass are driven by insulin sensitizing, secondary bile acids.

CONCLUSIONS: Overall findings suggest that bacterially derived bile acids may mediate the early improvements at one month after RYGB. Future studies should examine the changes in specific bile acid chemical species following bariatric procedures and bile acid-specific signaling changes.
PMID: 26196952 [PubMed - as supplied by publisher]

Source: Diabetes Metab - July 21, 2015 Category: Endocrinology Authors: Albaugh VL, Flynn CR, Cai S, Xiao Y, Tamboli RA, Abumrad NN Tags: J Clin Endocrinol Metab Source Type: research