Unique Genetic and Survival Characteristics of Invasive Mucinous Adenocarcinoma of the Lung

Conclusions: Our data suggest that mucinous adenocarcinoma is typified by (1) frequent KRAS mutations and a growing list of gene fusions, but rare TP53 mutations, (2) a low mutation burden overall, and (3) a recurrence-free survival similar to stage-matched nonmucinous tumors, with recurrences limited to the lungs.
Source: Journal of Thoracic Oncology - Category: Cancer & Oncology Tags: Original Article Source Type: research