Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid–sensing systems in rainbow trout

We hypothesized that food intake and the response of fatty acid (FA)-sensing systems in hypothalamus, liver, and Brockmann bodies of rainbow trout to raised levels of oleate (OL) or octanoate (OCT) is modified by insulin treatment. To assess this hypothesis, 15 fish per group received intraperitoneally 10-mL/kg injection of saline solution alone (control), or containing insulin (2-mg bovine insulin/kg body mass), OL (300 μg/kg), OCT (300 μg/kg), insulin + OL, or insulin + OCT to be sampled 6 h later to assess parameters related to FA sensing.

Source: Domestic Animal Endocrinology - July 2, 2015 Category: Endocrinology Authors: M. Librán-Pérez, C. Velasco, C. Otero-Rodiño, M.A. López-Patiño, J.M. Míguez, J.L. Soengas Source Type: research