Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody
In conclusion, no adverse reproductive or developmental effects were observed in rabbits following exposure to tabalumab at doses as high as 30 mg/kg and exposures at least 14‐fold greater than human exposure levels.
Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - Category: Perinatology & Neonatology Authors: William J. Breslin, Kim G. Hilbish, Jennifer A. Martin, Carolyn A. Halstead, Tammy L. Edwards Tags: Research Article Source Type: research
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