Treatment-resistant pediatric giant prolactinoma and multiple endocrine neoplasia type 1

Conclusions: This case emphasizes the need to consider pituitary adenomas in the differential diagnosis of all pediatric suprasellar tumors by careful endocrine assessment and measurement of at least a serum prolactin concentration. It also highlights the lack of evidence for the optimal management of pediatric drug-resistant prolactinomas. Finally, the case we describe demonstrates the importance of a detailed family history and the role of genetic testing for MEN1 and AIP mutations in all cases of pediatric pituitary adenoma.
Source: International Journal of Pediatric Endocrinology - Category: Endocrinology Authors: Source Type: research