Cetrorelix and Triptorelin active immunization influences follicle development and receptor expressions of ovaries in mice

In conclusion, Cetrorelix and Triptorelin immunization could improve ovarian growth, increase the follicle numbers, enhance dose-dependently the FLD, FTD and FWT, and eventually promote the ovary and follicle development. Cetrorelix decreased expression levels of FSHR and LHR proteins in the ovaries of mice. Triptorelin enhanced expression levels of FSHR and LHR proteins. Triptorelin treatment had more obvious effect than Cetrorelix. Graphical abstract
Source: Journal of Applied Biomedicine - Category: Biotechnology Source Type: research