Sensory neuron differentiation potential of in utero mesenchymal stem cell transplantation in rat fetuses with spina bifida aperta

CONCLUSIONOur results indicate that the transplantation of MSCs into the spinal cord could promote the transplanted MSCs and the surrounding cells to differentiate toward a sensory neuron cell fate and to play an important role in protecting sensory neurons in DRG. This approach might be of value in the treatment of sensory neuron deficiency in spina bifida aperta. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 14, 2015 Category: Perinatology & Neonatology Authors: Wei Ma, Xiaowei Wei, Hui Gu, Hui Li, Kaoping Guan, Dan Liu, Lizhu Chen, Songying Cao, Dong An, Henan Zhang, Tianchu Huang, Jianing Miao, Guifeng Zhao, Di Wu, Bo Liu, Weilin Wang, Zhengwei Yuan Tags: Original Research Article Source Type: research