Serum Cytokine Profiles of Patients with Interstitial Lung Disease Associated with anti-CADM-140/MDA5 antibody positive Amyopathic Dermatomyositis

Patients with amyopathic dermatomyositis (ADM) sometimes develop rapidly progressive interstitial lung disease (ILD) predominantly in Asia. Although anti-CADM-140/MDA5 antibody titer could correlate with disease activity and predict the course of ILD associated with ADM, it is not clear how this antibody is involved in the pathogenesis of ILD in ADM.

Source: Respiratory Medicine CME - July 9, 2015 Category: Respiratory Medicine Authors: Toshinori Takada, Ami Aoki, Katsuaki Asakawa, Takuro Sakagami, Hiroshi Moriyama, Ichiei Narita, Shinji Sato Source Type: research