Dose-volume relationship of acute and late small bowel toxicity from radiation therapy for prostate cancer: a Veterans Affairs study

Conclusion In this Veterans Affairs population of prostate cancer patients treated with radiation, V45 < 200 cc minimizes small bowel toxicity. However, we show this constraint can possibly be exceeded without significant short- and long-term complications. Further studies should explore maximum tolerated dose-volume relationship to maximize tumor control without increasing the small bowel toxicity profile.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research