Comparison of Different Techniques of Ultrasound-Guided Fine Needle Biopsy of Liver in a Swine Model

Conclusions: Among these three different FNB techniques, CFNB technique provided the greatest cellularity. Capillary-FNB technique was inferior among all with the lowest quality of obtained material for cytopathological interpretation.,Background: The quality of liver biopsy specimens obtained with different fine needle biopsy (FNB) techniques has not been compared.,Objectives: This study was performed to evaluate the diagnostic quality of three different liver FNB biopsy techniques.,Materials and Methods: Two sequential biopsy series were performed on piglets. Three biopsy techniques were compared: capillary-FNB, core-FNB (CFNB) and vacuum-assisted CFNB (VACFNB) in a swine model. Initially, 30 liver biopsies were performed (ten for each technique). The cellularity and quantity of blood in specimens were measured and compared. In the second series, 54 additional biopsies using CFNB and VACFNB techniques (27 each) in a separate piglet were evaluated in the same fashion.
Source: Hepatitis Monthly - Category: Infectious Diseases Source Type: research