4-Methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis

In conclusion, 4MU has antitumor activity in vivo and its mechanisms of action involve an inhibition of angiogenesis and IL-6 production. 4MU is an orally available molecule with potential for HCC treatment.

Source: Glycobiology - July 1, 2015 Category: Biology Authors: Piccioni, F., Fiore, E., Bayo, J., Atorrasagasti, C., Peixoto, E., Rizzo, M., Malvicini, M., Tirado-Gonzalez, I., Garcia, M. G., Alaniz, L., Mazzolini, G. Tags: Cancer Biology Source Type: research