Characterization of [123I]FP‐CIT binding to the dopamine transporter in the striatum of tree shrews by quantitative in vitro autoradiography

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Using in vitro autoradiography, the authors characterize the binding of [123I]FP‐CIT to striatal dopamine transporters in tree shrew compared to rat. This is the first report of the dissociation constant of [123I]FP‐CIT for the dopamine transporter in mammalian brain.

Source: Synapse - July 1, 2015 Category: Neurology Authors: Stefanie Geisler, Nicola Beindorff, Markus Cremer, Kerstin Hoffmann, Winfried Brenner, Paul Cumming, Philipp T. Meyer, Karl‐Josef Langen, Eberhard Fuchs, Ralph Buchert Tags: Research Article Source Type: research