Selective advantage of HLA matching in successful uncomplicated oocyte donation pregnancies

Oocyte donation (OD) was first introduced in 1984 (Lutjen et al., 1984) and enables women with various causes of reproductive failure to conceive. In their latest annual report on assisted reproductive therapies, the European Society of Human Reproduction and Embryology (ESHRE) published data on 20 countries performing oocyte donation (Kupka et al., 2014). A total of 15,825 fresh transfers after OD were performed, resulting in 6568 pregnancies, and giving a pregnancy rate of 47.4%. This pregnancy rate number is not associated with indication for the oocyte donation (Paulson et al., 1997).

Source: Journal of Reproductive Immunology - June 23, 2015 Category: Allergy & Immunology Authors: Lisa E.E.L.O. Lashley, Geert W. Haasnoot, Marijke Spruyt-Gerritse, Frans H.J. Claas Source Type: research