Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture

Conclusions This study shows that although HCLS1 expression was downregulated in MSCs of osteosarcoma patients and binucleate cells were present in both patient and donor derived MSCs, there was no evidence of neoplastic changes to occur during long-term culture.

http://link.springer.com/10.1186/s13569-015-0031-1

Source: Clinical Sarcoma Research - June 23, 2015 Category: Cancer & Oncology Source Type: research