Quantifying Parameter and Structural Uncertainty of Dynamic Disease Transmission Models Using MCMC: An Application to Rotavirus Vaccination in England and Wales

Conclusion. Accounting for the joint uncertainty of several vaccine characteristics resulted in more insight into which of these are crucial for determining the impact of rotavirus vaccination. Data for up to at least 10 y postvaccination and covering older children and adults are crucial to address remaining questions on the impact of widespread rotavirus vaccination.

Source: Medical Decision Making - June 16, 2015 Category: Health Management Authors: Bilcke, J., Chapman, R., Atchison, C., Cromer, D., Johnson, H., Willem, L., Cox, M., Edmunds, W. J., Jit, M. Tags: Original Articles Source Type: research