Complex and dynamic expression of cadherins in the embryonic marmoset cerebral cortex

In this study, to explore primate‐specific cadherin expression at the embryonic stage, we extensively analyzed the expression of these cadherins in the developing embryonic marmoset brain. Each cadherin showed differential spatial and temporal expression and exhibited temporally complicated expression. Furthermore, the expression of some cadherins differed from that in rodent brains, even at the embryonic stage. These results suggest the possibility that the differential expressions of diverse cadherins are involved in primate specific cortical development, from the prenatal to postnatal period.

Schematic representation of expression pattern of cadherins in the developing cortical plate of embryonic marmosets. Each cadherin shows a differential expression spatially and temporally.

Source: Development, Growth and Differentiation - June 1, 2015 Category: Research Authors: Eiji Matsunaga, Sanae Nambu, Mariko Oka, Atsushi Iriki Tags: Original Article Source Type: research