Hyperbaric Oxygen Preconditioning Attenuates Myocardium Ischemia-Reperfusion Injury Through Upregulation of Heme Oxygenase 1 Expression: PI3K/Akt/Nrf2 Pathway Involved

Conclusion: These data present a novel signaling mechanism by which hyperbaric oxygen preconditioning protects myocardium ischemia-reperfusion injury via PI3K/Akt/Nrf2-dependent antioxidant defensive system.

http://cpt.sagepub.com/cgi/content/abstract/20/4/428?rss=1

Source: Journal of Cardiovascular Pharmacology and Therapeutics - June 17, 2015 Category: Cardiology Authors: Yin, X., Wang, X., Fan, Z., Peng, C., Ren, Z., Huang, L., Liu, Z., Zhao, K. Tags: Experimental Studies Source Type: research