Genotype-Guided Dosing of Coumarin Anticoagulants: A Meta-analysis of Randomized Controlled Trials

Conclusions:
This meta-analysis showed that genotype-guided dosing increased the effectiveness and safety of coumarin therapy compared with standard dosing but did not have advantages compared with clinical variables-guided dosing.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - June 17, 2015 Category: Cardiology Authors: Tang, T., Liu, J., Zuo, K., Cheng, J., Chen, L., Lu, C., Han, S., Xu, J., Jia, Z., Ye, M., Pei, E., Zhang, X., Li, M. Tags: Clinical Studies Source Type: research