Case series: 11 hospital workers symptomatic after ingesting “synthetic marijuana” brownies

3 out of 5 stars Cluster of Acute Toxicity from Ingestion of Synthetic Cannabinoid-Laced Brownies. Obafemi AI et al. J Med Toxicol 2015 May 13 [Epub ahead of print] Abstract This case series describes 11 patients brought to hospital after inadvertently ingesting brownies laced with the synthetic cannabinoid AM-2201. All 11 patients were hospital workers who ingested brownies brought to work by a staff member. In each patient, symptoms started within an hour of ingestion and generally resolved within 2 to 4 hours (although two persons felt tired and dizzy for up to 10 hours post-ingestion.) The most common neurological manifestations included memory impairment (10/11) and inappropriate giggling (4/11.) All patients reported numbness and tingling, dry mouth, and lightheadedness. There were no gastrointestinal manifestations. All patients had negative routine urine drug screens. Laboratory analysis of a remaining brownie was positive for AM-2201. No analytical tests were done on biological specimens. Note that this report’s findings are not generalizable, since the next patient you see with exposure to a synthetic cannabinoid could have ingested an entirely different agent and/or a radically different dose. Your mileage may vary. And of course, whenever we refer to marijuana brownies — or even synthetic marijuana brownies — we have to replay this clip: Related post: First case of cycle emesis associated with synthetic cannabinoids   [Photo of brownie from en....
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical acute toxicity AM-2201 ingestion synthetic cannabinoid Source Type: news