MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene

Conclusions: These studies elucidate a new layer of regulation in the PI3K/AKT/mTOR pathway with relevance to mammary development and tumour progression and identify miR-184 as a putative breast tumour suppressor.

http://breast-cancer-research.com/content/17/1/83

Source: Breast Cancer Research - June 13, 2015 Category: Cancer & Oncology Authors: Yu PhuaAkira NguyenDaniel RodenBenjamin ElsworthNiantao DengIva NikolicJessica YangAndrea McfarlandRoslin RussellWarren KaplanMark CowleyRadhika NairElena ZotenkoSandra O¿TooleShi-xiong TanDavid JamesSusan ClarkHosein Kouros-MehrAlexander Swarbrick Source Type: research