Simple renal cysts and hypertension are associated with angiotensinogen (AGT) gene variant in Shiraz population (Iran)

Conclusions:
Our findings show a relationship between the AGT-TT genotype and hypertension in patients with both hypertension and simple renal cysts. This finding suggests an additive role for the AGT gene of the renin-angiotensin system in the process of hypertension and simple renal cysts formation. Future studies are needed to elucidate the mechanisms through which this association is mediated.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - June 12, 2015 Category: Biomedical Science Authors: Tabei, S., Nariman, A., Daliri, K., Roozbeh, J., Khezri, A., Goodarzi, H., Lotfi, M., Sefidbakht, S., Entezam, M. Tags: Original Articles Source Type: research