Vascular angiotensin II type 2 receptor attenuates atherosclerosis via a kinin/NO-dependent mechanism

Conclusions:
Vascular AT2 stimulation exerts anti-atherogenic actions in an endothelial kinin/NO-dependent manner, and its anti-oxidative effect is likely to be exerted by inhibiting the accumulation of superoxide-producing mononuclear leukocytes.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - June 12, 2015 Category: Biomedical Science Authors: Takata, H., Yamada, H., Kawahito, H., Kishida, S., Irie, D., Kato, T., Wakana, N., Miyagawa, S., Fukui, K., Matsubara, H. Tags: Original Articles Source Type: research