Inhibition of local aldosterone by eplerenone reduces renal structural damage in a novel model of chronic cyclosporine A nephrotoxicity

Conclusion:
Our results suggest local renal aldosterone is an important mediator of renal injury induced by CsA.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - June 12, 2015 Category: Biomedical Science Authors: Sun, Q.-L., Li, M., Rui, H.-L., Chen, Y.-P. Tags: Original Articles Source Type: research