Analysis of pre- and post-donation haematological values in plateletpheresis donors

Publication date: Available online 11 June 2015 Source:Apollo Medicine Author(s): Vandana Gite , Maruti Dhakane The post-procedure haematological values of donor in plateletpheresis have received relatively little attention. The present study is aimed to study reductions in haematological values after plateletpheresis. The total 100 successful plateletpheresis procedures were performed with Haemonetics® MCS® LN09000 – 220E/ED system at apheresis unit of tertiary care centre. To measure the pre- and post-donation haematological values, whole blood samples were collected in EDTA vials just before and within 30min after the procedure. Parameters, including Hb concentration, haematocrit, platelet and WBC counts, mean platelet volume (MPV), platelet distribution width (PDW), etc. were measured. The total mean reduction of 81.980×109 per litre in platelet count is noticed with mean pre-donation platelet count 312×109 per litre and mean post-donation platelet count 230×109 per litre. The total mean reduction of 0.85g/dL in total haemoglobin, decrease of 1.22% in HCT and reduction of 0.561 in ×109 per litre total WBC count are noticed. The total mean reduction of 0.2×1012 per litre in total RBC count, decrease of 0.57pg in MCH, decrease of 0.82g/dL in MCHC is noticed. P-value is statistically significant and <0.05. So it is recommended that apheresis donors with low normal pre-procedure platelet counts (150–200×109 per litre) and Hb concentration (12.5–13g/...
Source: Apollo Medicine - Category: Journals (General) Source Type: research