Effects of a prolonged infusion of fentanyl, with or without atropine, on the minimum alveolar concentration of isoflurane in dogs

Conclusions and clinical relevanceIn this study, fentanyl reduced the ISOMAC by approximately 50%. The ISOMAC remained stable throughout the 300 minute CRI of fentanyl, suggesting no cumulative effect of the opioid. Atropine did not influence ISOMAC in dogs.

Source: Veterinary Anaesthesia and Analgesia - June 8, 2015 Category: Veterinary Research Authors: Clarissa R Simões, Eduardo R Monteiro, Julia PP Rangel, Juarez S Nunes‐Junior, Daniela Campagnol Tags: Research Paper Source Type: research