Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia-reperfusion injury.

In conclusion, sevoflurane pretreatment alleviated lung permeability by upregulating occludin and ZO-1 after ischemia-reperfusion. Sevoflurane pretreatment inhibited the translocation and activation of PKC-α, which also contributed to the lung-protective effect of sevoflurane. PMID: 26045255 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26045255?dopt=Abstract

Source: exp Mol Med - June 7, 2015 Category: Molecular Biology Authors: Chai J, Long B, Liu X, Li Y, Han N, Zhao P, Chen W Tags: Exp Mol Med Source Type: research