Blood alanine aminotransferase levels >1,000 IU/l - causes and outcomes.

In this study, we have confirmed that the main causes of a dramatic ALT rise are ischaemic liver injury, DILI and viral hepatitis. Common bile duct stones and hepatitis E are two causes for which there needs to be a high index of suspicion as the necessary tests may not be in the clinician's first-line investigation panel. Failing to find a cause and determining that the cause was ischaemic both have poor prognostic implications. PMID: 26031973 [PubMed - in process]
Source: Clinical Medicine - Category: Journals (General) Authors: Tags: Clin Med Source Type: research