Current status of chemically synthesized inhibitors of ebola virus.

Current status of chemically synthesized inhibitors of ebola virus. Recent Pat Antiinfect Drug Discov. 2014;9(2):97-103 Authors: Cardile AP, Mayers DL, Bavari S Abstract The current Ebola virus outbreak is unprecedented in its scope and international impact. Given that there are currently no approved antivirals to treat Ebola virus, there is urgency to conduct more rapid development and evaluation of Ebola antivirals. Recently, the World Health Organization identified a number of antivirals as high priority to include AVI-6002 (AVI-7537 and AVI-7539), BCX4430, brincidofovir, favipiravir, and TKM-100802. This review describes these chemically synthesized inhibitors of Ebola virus, relevant patent development and gives an update on their current status. PMID: 25808170 [PubMed - in process]
Source: Recent Patents on Anti-Infective Drug Discovery - Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research