Pharmacoperones: a new therapeutic approach for diseases caused by misfolded G protein-coupled receptors.

This article reviews some patents and new therapeutic opportunities based on the misfolding and retention of otherwise functional GPCRs that represent promising approaches to correct conformational abnormalities leading to distinct disease states. PMID: 22074574 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/22074574?dopt=Abstract

Source: Recent Patents on Endocrine, Metabolic and Immune Drug Discovery - June 4, 2015 Category: Endocrinology Tags: Recent Pat Endocr Metab Immune Drug Discov Source Type: research

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