The hypothalamic-neurohypophyseal system: current and future treatment of vasopressin and oxytocyn related disorders.

The hypothalamic-neurohypophyseal system: current and future treatment of vasopressin and oxytocyn related disorders. Recent Pat Endocr Metab Immune Drug Discov. 2012 Sep;6(3):235-50 Authors: Calabrò RS, Italiano D, Ferrara D, Mondello S, Conti-Nibali V, Salviera C, Bramanti P Abstract The hypothalamus and posterior pituitary form a complex neurohumoral system playing a key role in maintaining body fluid homeostasis and reproductive function. We review the pathophysiology mechanisms of posterior pituitary hormones and their implications, beyond water balance and delivery, in social functioning, pair bonding and affiliative behavior. Actual and future treatments for neurohypophysis related disorders are also discussed, particularly focusing on the development of new therapeutic compounds and patents. PMID: 22827638 [PubMed - indexed for MEDLINE]
Source: Recent Patents on Endocrine, Metabolic and Immune Drug Discovery - Category: Endocrinology Tags: Recent Pat Endocr Metab Immune Drug Discov Source Type: research