MAVS: a new weapon in the fight against viral infections.

MAVS: a new weapon in the fight against viral infections. Recent Pat Endocr Metab Immune Drug Discov. 2013 May;7(2):115-9 Authors: Boga JA, de Oña M, Melon S, Alvarez-Arguelles ME, Morilla A, Coto-Montes A Abstract In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review. PMID: 23432157 [PubMed - indexed for MEDLINE]
Source: Recent Patents on Endocrine, Metabolic and Immune Drug Discovery - Category: Endocrinology Tags: Recent Pat Endocr Metab Immune Drug Discov Source Type: research