Responsibility study: main illicit psychoactive substances among car drivers involved in fatal road crashes.

Responsibility study: main illicit psychoactive substances among car drivers involved in fatal road crashes. Ann Adv Automot Med. 2011;55:293-300 Authors: Gadegbeku B, Amoros E, Laumon B Abstract In 1999, in France, before considering modifications in drug legislation, the government requested a study of the effect of illicit drugs on the risk of road crashes. It implemented a systematic screening of illicit drugs for all drivers involved in fatal crashes between October 2001 and September 2003. Within the European DRUID project, the study was restricted to car drivers.The project reported here is a responsibility analysis and, as such, it belongs to the framework of case-control studies; the outcome of interest is "being responsible for a fatal crash". It was assessed with a method adapted from Robertson and Drummer. Cases are the 4,946 car drivers who are responsible for the crash; controls are the 1,986 car drivers selected from the non-responsible car drivers, in a way that makes the control group similar to the general driving population.The effect of cannabis on fatal crash responsibility is significant after adjustment for age, sex and alcohol: adjusted odds ratio is 1.89 [1.43-2.51]. The dose-response effect is significant (p=0.0001). For alcohol (≥0.1 g/l), the adjusted odds ratio for responsibility is 8.39 [6.95-10.11]. No interaction was found between alcohol and cannabis. For amphetamine, cocaine and opiates, adjusted o...
Source: Annals of Advances in Automotive Medicine - Category: Global & Universal Tags: Ann Adv Automot Med Source Type: research