Citric acid 50% solution versus tretinoin 0.05% lotion in the treatment of plane warts

Background: The course of human papilloma virus infection varies considerably and there are many modalities of therapy, reflecting that none is uniformly effective. Objective: To evaluate and compare the efficacy of 50% citric acid solution in water versus 0.05% tretinoin lotion for the treatment of plane wart in a sample of Egyptian patients. Patients and methods: Ninety patients with plane warts were included in this randomized comparative therapeutic study with age range from 7 to 34 years. The selected patients were divided into two treatment groups, wherein group I applied 50% citric acid solution twice daily and group II applied 0.05% tretinoin lotion once daily for 8 weeks or till complete clearance. The follow-up time was 3 weeks after the final treatment. Results: There was a statistically significant difference (P
Source: Journal of the Egyptian Women’s Dermatologic Society - Category: Dermatology Tags: Original articles Source Type: research