Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures

Conclusions: Collectively, the pilot data is consistent with the notion that increased blood is supplied to breast cancers, and it also suggests that less conversion of oxy- to deoxy-hemoglobin occurs in more proliferative cancers. Overall, the observations corroborate expectations that macroscopic measurements of breast cancer physiology using DOT and DCS can reveal microscopic pathological properties of breast cancer and hold potential to complement pathological biomarker information.
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Source Type: research