Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion

Recurrent spontaneous abortion (RSA) is defined as three or more consecutive spontaneous miscarriages before the 20 week of pregnancy (Ford and Schust, 2009) and is a common condition in obstetrics and gynecology, affecting 2–5% of couples attempting to reproduce (Branch et al., 2010). RSA seriously influences patients’ physical and mental health. RSA has been recognized as a worldwide problem with numerous causes, including parental chromosomal abnormalities, uterine abnormalities, hereditary thrombophilia, endocrine disorders, immunological factors, and/or infections (Kiwi, 2006).
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research