Maternal Pro12Ala polymorphism is associated with infant's neurodevelopmental outcomes at 18months of age

Peroxisome proliferator activated receptors (PPARs) are ligand activated transcription factors with crucial functions in lipid homeostasis, glucose metabolism, anti-inflammatory processes, placental development, and are involved in cognitive functions and neurodegenerative diseases. Polymorphisms in PPAR genes are shown to influence the activity of these receptors.

Source: Early Human Development - May 28, 2015 Category: Perinatology & Neonatology Authors: Francisco J. Torres-Espínola, Signe Altmäe, Maria Teresa Segura, Antonio Jerez, Tania Anjos, Maribel Chisaguano, M. Carmen López-Sabater, Carmen Entrala, Juan Carlos Alvarez, Ahmad Agil, Jesus Florido, Andres Catena, Miguel Pérez-García, Cristina Cam Source Type: research