Usual interstitial pneumonia end-stage features from explants with radiologic and pathological correlations

Idiopathic pulmonary fibrosis (IPF) is the most frequent and severe idiopathic interstitial pneumonia, with typical high-resolution computed tomography (HRCT) features and histologic pattern of usual interstitial pneumonia (UIP); its main differential diagnosis is fibrotic nonspecific interstitial pneumonia (F-NSIP). Usual interstitial pneumonia was mainly described from lung biopsies, and little is known on explants. Twenty-two UIP/IPF explants were analyzed histologically and compared with previous open lung biopsies (OLBs; n = 11) and HRCT (n = 19), when available.

Source: Annals of Diagnostic Pathology - May 13, 2015 Category: Pathology Authors: Maud Rabeyrin, Françoise Thivolet, Gilbert R. Ferretti, Lara Chalabreysse, Adrien Jankowski, Vincent Cottin, Christophe Pison, Jean-François Cordier, Sylvie Lantuejoul Tags: Radiologic-Pathologic Correlation Source Type: research