Investigation of Proposed Mechanisms of Chemotherapy-Induced Venous Thromboembolism: Endothelial Cell Activation and Procoagulant Release Due to Apoptosis

Conclusions: During chemotherapy for breast cancer, VECA is induced; however, this is not the primary mechanism for VTE. Chemotherapy-induced apoptosis may enhance hypercoagulability and initiate VTE.

Source: Clinical and Applied Thrombosis/Hemostasis - May 26, 2015 Category: Hematology Authors: Kirwan, C. C., McCollum, C. N., McDowell, G., Byrne, G. J. Tags: Original Articles Source Type: research