Histological characteristics of the myometrium in the postpartum hemorrhage of unknown etiology: possible involvement of local immune reactions

Postpartum hemorrhage (PPH) is the leading cause of maternal mortality in the world, with an incidence estimated to be up to 10% (Oyelese et al., 2007, Mousa et al., 2014, Cunningham et al., 2010). Various conditions such as abnormal placentation, trauma to the genital tract, uterine atony, and coagulation defects are known causes of PPH (Cunningham et al., 2010). Among the above, uterine atony is a major cause of PPH, estimated to be responsible for 70% (Karoshi and Keith, 2009, Oyelese and Ananth, 2010); however, the etiology remains to be clarified in cases of PPH secondary to uterine atony.

Source: Journal of Reproductive Immunology - May 20, 2015 Category: Allergy & Immunology Authors: Mustari Farhana, Naoaki Tamura, Mari Mukai, Kotomi Ikuma, Yukiko Koumura, Naomi Furuta, Chizuko Yaguchi, Toshiyuki Uchida, Kazunao Suzuki, Kazuhiro Sugihara, Hiroaki Itoh, Naohiro Kanayama Source Type: research