Soluble hla-g in pregnancies complicated by autoimmune rheumatic diseases

Autoimmune rheumatic diseases in pregnancy are associated with increased rates of pre-eclampsia, impaired fetal growth, prematurity, neonatal autoimmune diseases, congenital heart block, and stillbirth (Andreoli et al., 2010, Brucato et al., 2011, Ostensen et al., 2011, Canti et al., 2012). Early in the first trimester of pregnancy it is possible to identify subjects with markers of rheumatic diseases who are at risk for subsequent pregnancy complications (Spinillo et al., 2008a, 2008b, 2012). The interaction between pregnancy and rheumatic diseases is complex.

Source: Journal of Reproductive Immunology - May 20, 2015 Category: Allergy & Immunology Authors: Fausta Beneventi, Carla Badulli, Elena Locatelli, Roberto Caporali, Véronique Ramoni, Chiara Cavagnoli, Margherita Simonetta, Giulia Garbin, Carmine Tinelli, Claudia Alpini, CarloMaurizio Montecucco, Miryam Martinetti, Arsenio Spinillo Source Type: research