Could misoprostol improve intestinal motility in women who had cesarean section?

Aim: We assessed whether there is an effect of rectal misoprostol (a prostaglandin E1 analogue) on intestinal motility in women who had cesarean sections. Patients and methods: A total of 120 women who had an elective cesarean section under spinal anesthetic were recruited for a randomized controlled trial. They were randomized into three groups: group A, who did not take misoprostol; group B, who took 200 μg misoprostol; and group C, who took 400 μg misoprostol. We compared the three groups with respect to time to pass flatus, time till the bowel sounds were heard, time to start regular diet, and side effects of misoprostol. Results: No statistical difference was seen as regard age, parity, BMI, number of previous cesarean sections, and duration of surgery. There was no statistical difference with regard to the presence of bowel sounds, but time to pass flatus and time to start regular diet were significantly shorter in the group who did not take misoprostol (P
Source: Journal of Evidence-Based Women’s Health Journal Society - Category: OBGYN Tags: Original articles Source Type: research