Sodium channel NaV1.7 in vascular myocytes, endothelium, and innervating axons in human skin

Conclusions: These observations suggest that the activity of mutant Nav1.7 channels in smooth muscle cells of skin vasculature and innervating sensory and sympathetic fibers contribute to the skin reddening and/or pain in IEM and PEPD.
Source: Molecular Pain - Category: Molecular Biology Authors: Source Type: research