The effect of thyroid autoimmunity on t-cell responses in early pregnancy

Thyroid autoimmunity (TAI) is the most common autoimmune disorder, affecting 5–20% of the female population during their reproductive period (McLeod and Cooper, 2012). It is the main cause of overt or subclinical hypothyroidism in women of childbearing age (Poppe et al., 2008). There is considerable evidence for the association between TAI, with or without thyroid dysfunction, and menstrual irregularities, fertility problems, and increased morbidity in pregnancy (Kennedy et al., 2010, Lazzarin et al., 2012, Bagis et al., 2001).

Source: Journal of Reproductive Immunology - May 8, 2015 Category: Allergy & Immunology Authors: Ozlem Turhan Iyidir, Ceyla Konca Degertekin, Cemile Sonmez, Ayşegül Atak Yucel, Mehmet Erdem, Mujde Akturk, Goksun Ayvaz Source Type: research