Biomonitoring of the Genotoxic and Hepatotoxic Effects and Oxidative Stress Potentials of Itraconazole in Pregnant Rats

CONCLUSIONThese findings indicate that itraconazole administration at doses of 75, 100, or 150 mg/kg during pregnancy induced maternal and fetal toxicity that could be induced by the genotoxicity and the oxidative damage

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - February 1, 2015 Category: Perinatology & Neonatology Authors: Abdel‐Fattah El‐Shershaby, Ahmed I. Dakrory, Mai H. El‐Dakdoky, Jehane Ibrahim, Fatma Kassem Tags: Research Article Source Type: research