Photoperiod affects the cerebrospinal fluid proteome: a comparison between short day- and long day-treated ewes

Photoperiod is the main physical synchronizer of seasonal functions and a key factor in the modulation of molecule access to cerebrospinal fluid (CSF) in animals. Previous work has shown that photoperiod affects the transfer rate of steroids and protein hormones from blood to CSF and modulates choroid plexus (CP) tight junction protein content. We hypothesized that the CSF proteome would also be modified by photoperiod. We tested this hypothesis by comparing CSF obtained from the third ventricle of mature, ovariectomized, estradiol-replaced ewes exposed to long day length (LD) or short day length (SD).

Source: Domestic Animal Endocrinology - April 27, 2015 Category: Endocrinology Authors: A.-P. Teixeira-Gomes, G. Harichaux, D. Gennetay, J. Skipor, J.-C. Thiery, V. Labas, L. Dufourny Source Type: research