Effect of Aldosterone on Epithelial-to-Mesenchymal Transition of Human Peritoneal Mesothelial Cell

Conclusion Aldosterone induced EMT in HPMC by acting through mineralocorticoid receptor. Aldosterone-induced generation of ROS followed by an activation of ERK & p38 MAPK served as one of the mechanisms of aldosterone-induced EMT of HPMC.
Source: Kidney Research and Clinical Practice - Category: Urology & Nephrology Source Type: research