Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells

Conclusion: Our results suggest the significance of STAT3 activation in the maintenance and survival of ovarian cancer cells. The activated STAT3 signaling is the critical molecular target of resveratrol. Resveratrol would be a promising candidate in the management of ovarian cancers, especially the ones with resistance to conventional therapeutic agents.

http://www.ovarianresearch.com/content/8/1/25

Source: Journal of Ovarian Research - April 22, 2015 Category: Cancer & Oncology Authors: Li-Xia ZhongHong LiMo-Li WuXiao-Yu LiuMing-Jun ZhongXiao-Yan ChenJia LiuYang Zhang Source Type: research