Off-Label Use of Gastrointestinal Medications in the Intensive Care Unit

Conclusion:
The PPIs are the most widely used off-label medications in the ICU. Stress ulcer prophylaxis is the most common indication. The level of evidence supporting off-label GI medication use is poor.

Source: Journal of Intensive Care Medicine - April 20, 2015 Category: Intensive Care Authors: Barletta, J. F., Lat, I., Micek, S. T., Cohen, H., Olsen, K. M., Haas, C. E., Critical Care Pharmacotherapy Trials Network Tags: Review of a Large Clinical Series Source Type: research