Primary cilia modulate balance of canonical and non-canonical Wnt signaling responses in the injured kidney

Conclusions: We provide evidence that in the context of renal injury, primary cilia act as molecular switches between canonical and non-canonical Wnt signaling activity, possibly determining between regenerative and pro-fibrotic effects of Wnt re-expression in the injured kidney.
Source: Fibrogenesis and Tissue Repair - Category: Biomedical Science Authors: Source Type: research