The Cardio-Renal Syndrome (CRS)

Publication date: Available online 17 April 2015 Source:IJC Metabolic & Endocrine Author(s): Enrico V. Scabbia , Luca Scabbia The presence of impaired kidney function during heart failure and vice versa is a frequent occurrence. This situation is defined “Cardio-Renal Syndrome”. In the Cardio-Renal Syndrome (CRS) are included 5 different sub-syndromes defined on the basis of the organ primitively responsible: Acute Cardio-Renal Syndrome (Type 1), Chronic Cardio-Renal Syndrome (Type 2), Acute Reno-Cardiac Syndrome (Type 3), Chronic Renal-Cardiac Syndrome (Type 4) and Secondary Cardio-Renal Syndrome (Type 5). The physiopathologic mechanisms underlying CRS are still partially obscure, but , a key role seems to be played by the Renin-Angiotensin-Aldosterone axis. Therapeutic strategies involved in CRS treatment include the use of diuretics, ACE inhibitors, Angiotensin Receptor Blockers and β-Blockers, emphasizing the role of a proper use of medication indicated for the treatment of cardiac decompensation.
Source: IJC Metabolic and Endocrine - Category: Endocrinology Source Type: research